National Clinical Assessment (NCA) Cellular Practice Exam

The first step in managing heparin-induced thrombocytopenia (HIT) is to stop the heparin drip and give protamine sulfate. When HIT is suspected or diagnosed, the immediate cessation of heparin is critical because it is the trigger for the condition. Continuing heparin can exacerbate the low platelet count and increase the risk of thrombosis, which is counterproductive.

Administering more heparin would further compromise the patient, as it can lead to a worsening of the immunologic reaction and its complications. Starting platelet infusions is not a viable option in the context of HIT, as it does not address the underlying issue and may even pose additional risks. A splenectomy is generally a procedure considered in cases of other conditions affecting platelet counts but is not a standard acute management step for HIT.

In summary, the key to effective HIT management begins with halting heparin and using protamine sulfate, if necessary, to counteract any heparin effects, thus prioritizing patient safety and initiating the appropriate course of action.