Which intervention involves the collection of biological samples during a suspected transfusion reaction?

The collection of biological samples during a suspected transfusion reaction is critical for diagnosing the cause and ensuring proper medical response. In this context, obtaining urine and blood samples is vital because these samples can help identify hemolysis, electrolyte imbalances, and other transfusion-related complications.

Blood samples can reveal hemolytic reactions or other issues, such as ABO incompatibility or the presence of antibodies. Urine samples may show hemoglobinuria or other abnormalities that can occur as a result of hemolysis, shedding light on the severity of the reaction and guiding further treatment. This comprehensive approach to sample collection allows healthcare professionals to assess the patient's condition accurately and address any complications that may arise from the transfusion.

While the other options represent important interventions during a transfusion reaction, they do not directly involve the collection of biological samples. Infusing normal saline with tubing might be necessary for maintaining venous access or flushing the line, monitoring vital signs is crucial for assessing the patient’s immediate response to the transfusion, and notifying the provider and blood bank is essential for initiating proper protocols in case of a reaction. However, none of these actions directly address the need for biological samples essential for diagnosing the suspected reaction.