Which statement regarding skin reactions from chemotherapy is true?

The statement highlighting the importance of avoiding temperature extremes on affected skin is based on established practices in managing skin reactions induced by chemotherapy. Chemotherapy can lead to skin sensitivity and irritation. Exposure to extreme temperatures—either too hot or too cold—can exacerbate these conditions, causing additional discomfort or worsening the skin's reaction. Maintaining a stable, moderate temperature helps to protect the skin and promote recovery, making this approach a recommended practice for patients experiencing skin reactions while undergoing chemotherapy.

The other options do not align with best practices or evidence-based guidelines for managing chemotherapy-induced skin reactions. For instance, applying perfumed lotions can potentially irritate sensitive skin, rather than soothe it, as fragrances can contain allergens or irritating substances. The claim that skin reactions are unrelated to the treatment dose is inaccurate; indeed, the severity and type of skin reactions can often correlate with the dosage and type of chemotherapy administered. Lastly, while some mild skin reactions may resolve independently, many require proactive intervention to prevent complications and promote healing, making it incorrect to assert that all reactions will resolve without any intervention.