Which treatment is appropriate for managing osteoporosis in multiple myeloma?

In the context of managing osteoporosis in patients with multiple myeloma, the use of corticosteroids and chemotherapy is an appropriate treatment strategy. Multiple myeloma often leads to weakened bones, making them more susceptible to fractures and osteoporosis. Corticosteroids are frequently used in the treatment of multiple myeloma due to their anti-inflammatory and immunosuppressive properties, which help manage symptoms and exert effects on the underlying cancer.

Additionally, chemotherapy contributes to treating the myeloma itself, which is crucial since reducing the tumor burden can help alleviate some of the metabolic consequences of the disease on bone health. While these interventions can have adverse effects on bone density if used over extended periods, they also serve to manage the underlying condition effectively, thereby indirectly aiding bone health in the long term.

Other options like increased physical activity, strict bed rest, and increased calcium intake alone do not sufficiently address the complexity of osteoporosis in the context of active multiple myeloma. Increased physical activity needs to be balanced with the risk of fractures, while strict bed rest can exacerbate bone density loss. Increased calcium intake is essential, but it should be part of a broader treatment plan involving medications that target both myeloma and bone health.